Thimann, Kenneth V. and Beadle, G. W. (1937) Development of Eye Colors in Drosophila: Extraction of the Diffusible Substances Concerned. Proceedings of the National Academy of Sciences of the United States of America, 23 (3). pp. 143-147. ISSN 0027-8424 http://resolver.caltech.edu/CaltechAUTHORS:THIpnas37
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The development of eye color in Drosophila is known to involve special diffusible substances [1,2]. A genetically vermilion (v) eye will develop wild-type eye color if it is supplied with v+ substance by transplantation or by injection of body fluid of wild type flies. Similarly a genetically cinnabar (cn) eye will develop the color characteristic of wild type if it is supplied with cn+ substance. The present paper summarizes preliminary experiments made to learn something of the nature of the two substances just mentioned. During the course of our studies, Ephrussi and Harnly  have shown that pupal fluid can be freed of living cells by freezing in liquid air without destroying the v+ and cn+ substances. Khouvine, Ephrussi and Harnly  have shown further that these substances can be extracted from Calliphora pupae with 95 per cent alcohol-ether mixtures and with 95 per cent alcohol but not with pure ether. They conclude that these substances are not proteins or enzymes, a conclusion confirmed by our work.
|Additional Information:||Copyright © 1937 by the National Academy of Sciences. Communicated January 25, 1937.|
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|Deposited On:||01 May 2008|
|Last Modified:||26 Dec 2012 09:59|
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