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Poly(A) on mengovirus RNA

Spector, Deborah H. and Baltimore, David (1975) Poly(A) on mengovirus RNA. Journal of Virology, 16 (4). pp. 1081-1084. ISSN 0022-538X. http://resolver.caltech.edu/CaltechAUTHORS:SPEjvir75c

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Abstract

The content and size of the poly(A) on Mengovirus RNA grown in both mouse L cells and HeLa cells have been examined. Virion RNA from either cell line could bind to poly(U) filters and contained RNase-resistant stretches of poly(A) which could be analyzed by electrophoresis in polyacrylamide gels. The size of the poly(A) on the Mengovirus RNA was independent of the host cell and averaged from 50 to 70 nucleotides.


Item Type:Article
Additional Information:Copyright © 1975 by the American Society for Microbiology. Received for publication 17 June 1975. We thank Peter Plagemann for providing materials and for useful discussions. This work was supported by grant A108388 from the National Institute of Allergy and Infectious Diseases and by grant CA 14051 from the National Cancer Institute. D.H.S. was a predoctoral fellow of the National Science Foundation for part of this work. D.B. is an American Cancer Society Research Professor.
Record Number:CaltechAUTHORS:SPEjvir75c
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:SPEjvir75c
Alternative URL:http://jvi.asm.org/cgi/content/abstract/16/4/1081
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:10896
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:15 Jun 2008
Last Modified:26 Dec 2012 10:06

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