Borsook, Henry and Dubnoff, Jacob W. (1947) The hydrolysis of phosphocreatine and the origin of urinary creatinine. Journal of Biological Chemistry, 168 (2). pp. 493-510. ISSN 0021-9258 http://resolver.caltech.edu/CaltechAUTHORS:BORjbc47b
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Shaffer (1), Myers and Fine (2), and Hahn and Meyer (3) adduced evidence that muscle creatine is the precursor of urinary creatinine. This was questioned by Chanutin and Kinard (4) but was conclusively proved by Bloch, Schoenheimer, and Rittenberg (5, 6) by isotope tracer evidence, which also showed that creatinine was the only normal urinary constituent containing any significant amount of body creatine nitrogen (1).
|Additional Information:||© 1947 American Society of Biological Chemists. Received for publication, January 29, 1947.|
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|Deposited By:||Tony Diaz|
|Deposited On:||01 Oct 2008 05:35|
|Last Modified:||26 Dec 2012 10:19|
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