Borsook, Henry and Dubnoff, Jacob W. (1947) Methionine formation by transmethylation in vitro. Journal of Biological Chemistry, 169 (2). pp. 247-258. ISSN 0021-9258 http://resolver.caltech.edu/CaltechAUTHORS:BORjbc47e
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We reported in a previous communication (1) that guanidoacetic acid is methylated to creatine by rat liver slices in the presence of choline and either homocysteine or homocystine. Choline, homocystine, or homocysteine alone had little or no effect. These observations closed the gap which had existed between the evidence from tissue slice experiments on the one hand (2) and that from experiments in viva on the other (3-5) regarding the transfer of choline methyl in the formation of creatine.
|Additional Information:||© 1947 American Society of Biological Chemists. Received for publication, February 8, 1947. The authors wish to acknowledge the assistance of Miss I. Silberbach in the experiments reported here.|
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|Deposited By:||Tony Diaz|
|Deposited On:||02 Oct 2008 01:57|
|Last Modified:||26 Dec 2012 10:20|
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