CaltechAUTHORS
  A Caltech Library Service

A proposal for the structure of the Drosophila genome

Bonner, James and Wu, Jung-Rung (1973) A proposal for the structure of the Drosophila genome. Proceedings of the National Academy of Sciences of the United States of America, 70 (2). pp. 535-537. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:BONpnas73

[img]
Preview
PDF - Published Version
See Usage Policy.

620Kb

Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:BONpnas73

Abstract

We propose a structure for the genome of Drosophila melanogaster in which each chromatid of each chromomere (band) consists on the average of about 30-35 different sequences of single-copy (unique) DNA, each on the average about 750 base pairs in length. These are separated from one another by stretches of the middle repetitive (reiterated) DNA, which in D. melanogaster makes up about 15% of the genome. These stretches are about 100-150 base pairs in length and are all of the same sequence or family in each individual chromomere and of a different family (sequence) in each different chromomere. Our proposed structure of the Drosophila genome is in accord with all of the known facts concerning the physical chemistry and molecular biology of Drosophila DNA.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.pnas.org/content/70/2/535.abstractPublisherUNSPECIFIED
Additional Information:© 1973 by the National Academy of Sciences. Contributed by James Bonner, December 11, 1972. We thank Profs. Eric Davidson, Norman Davidson, and Edward Lewis for their suggestions, advice and counsel, and Prof. Norman Davidson for his tutorials in statistical calculations. This work was supported in part by U.S. Public Health Service Research Grant GM-13762 and in part by a postdoctoral fellowship of the U.S. Public Health Service (J.-R.W.).
Funders:
Funding AgencyGrant Number
Public Health ServiceGM-13762
Subject Keywords:repetitive DNA; unique DNA; chromomere; circle formation; chromosome structure
Record Number:CaltechAUTHORS:BONpnas73
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:BONpnas73
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:11910
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:16 Oct 2008 22:12
Last Modified:26 Dec 2012 10:23

Repository Staff Only: item control page