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The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development

Ohno, Carolyn K. and Reddy, G. Venugopala and Heisler, Marcus G. B. and Meyerowitz, Elliot M. (2004) The Arabidopsis JAGGED gene encodes a zinc finger protein that promotes leaf tissue development. Development, 131 (5). pp. 1111-1122. ISSN 0950-1991. http://resolver.caltech.edu/CaltechAUTHORS:OHNdev04

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Abstract

Important goals in understanding leaf development are to identify genes involved in pattern specification, and also genes that translate this information into cell types and tissue structure. Loss-of-function mutations at the JAGGED (JAG) locus result in Arabidopsis plants with abnormally shaped lateral organs including serrated leaves, narrow floral organs, and petals that contain fewer but more elongate cells. jag mutations also suppress bract formation in leafy, apetala1 and apetala2 mutant backgrounds. The JAG gene was identified by map-based cloning to be a member of the zinc finger family of plant transcription factors and encodes a protein similar in structure to SUPERMAN with a single C2H2-type zinc finger, a proline-rich motif and a short leucine-rich repressor motif. JAG mRNA is localized to lateral organ primordia throughout the plant but is not found in the shoot apical meristem. Misexpression of JAG results in leaf fusion and the development of ectopic leaf-like outgrowth from both vegetative and floral tissues. Thus, JAG is necessary for proper lateral organ shape and is sufficient to induce the proliferation of lateral organ tissue.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1242/10.1242/dev.00991DOIUNSPECIFIED
http://dev.biologists.org/cgi/content/abstract/131/5/1111PublisherUNSPECIFIED
Additional Information:Published by The Company of Biologists 2004. Accepted 18 November 2003. First published online February 18, 2004. We thank Jennifer Li and Stefan Wenkel for valuable assistance with positional mapping analysis, John Bowman for providing plant lines, and Marcio Alves Ferreira, Catherine Baker, Pradeep Das, Annick Dubois, Liz Haswell, Toshiro Ito, Jeff Long, Patrick Sieber, Frank Wellmer, and Hao Yu for critical comments on the manuscript. We also thank José Dinneny and Detlef Weigel for coordinating their publication with ours. C.O. received a postdoctoral fellowship from NSERC and G.V.R. is a fellow of the Jane Coffin Childs memorial fund for medical research. This work was supported by US National Science Foundation grant IBN-0211670 to E.M.M.
Funders:
Funding AgencyGrant Number
Natural Sciences and Engineering Research Council (NSCERC) (UK)UNSPECIFIED
Jane Coffin Childs Memorial Fund for Medical ResearchUNSPECIFIED
National Science FoundationIBN-0211670
Subject Keywords:JAGGED, Lateral organ growth, Leaf morphogenesis, Leaf development, Arabidopsis thaliana
Record Number:CaltechAUTHORS:OHNdev04
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:OHNdev04
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:12069
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:21 Oct 2008 22:39
Last Modified:26 Dec 2012 10:26

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