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A spectrophotometric study of blood group A-specific substance isolated from hog gastric mucosa

Holzman, George and Niemann, Carl (1948) A spectrophotometric study of blood group A-specific substance isolated from hog gastric mucosa. Journal of Biological Chemistry, 174 (1). pp. 305-318. ISSN 0021-9258. http://resolver.caltech.edu/CaltechAUTHORS:HOLjbc48

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Abstract

A study of the ultraviolet absorption spectra of preparations of blood group A-specific substance isolated from hog gastric mucin supports the view that group A substance, and probably group O substance, has little specific absorption in this spectral region and that other components account for most if not all of the specific absorption noted in the case of impure preparations. However, ultraviolet spectrophotometric analyses have been found to be particularly useful in following changes in composition brought about by the fractionation of group A substance preparations obtained from hog gastric mucin as well as in comparing preparations isolated by different methods and from different sources. Such analyses have also indicated that tyrosine and tryptophan, if indeed present in group A substance, are but minor constituents.


Item Type:Article
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http://www.jbc.org/content/vol174/issue1/index.dtlPublisherUNSPECIFIED
Additional Information:Copyright © 1948 American Society of Biological Chemists. (Received for publication, January 12, 1948) Gates and Crellin Laboratories of Chemistry, Contribution No. 1171
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Gates and Crellin Laboratories of Chemistry1171
Record Number:CaltechAUTHORS:HOLjbc48
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:HOLjbc48
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:12597
Collection:CaltechAUTHORS
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Deposited On:15 Dec 2008 17:44
Last Modified:26 Dec 2012 10:36

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