Aladjem, Frederick and Lieberman, Miriam and Gofman, W. (1957) Immunochemical studies on human plasma lipoproteins. Journal of Experimental Medicine, 105 (1). pp. 49-67. ISSN 0022-1007 http://resolver.caltech.edu/CaltechAUTHORS:ALAjem57
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Some years ago, a series of human serum lipoproteins, distinguishable by their hydrated densities and lipid-protein ratios were recognized and isolated by ultracentrifugal techniques (1). Certain of these lipoproteins are invariably present in human serum and the concentrations of these and of others can be quantitatively correlated with disease (2). No difference in the lipoprotein distribution can be demonstrated between serum and plasma. The purpose of this investigation was to obtain information about the immunochemical specificity of some of the lipoproteins.
|Additional Information:||Copyright, 1957, by The Rockefeller Institute for Medical Research New York. RUP grants the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. (Received for publication, August 20, 1956) We wish to acknowledge the many helpful discussions with our friends at Donner Laboratory, University of California, Berkeley, and at the Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, particularly the stimulating discussions with Professor Dan H. Campbell. This work was supported in part by the Life Insurance Medical Research Fund and the United States Public Health Service.|
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