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Spike frequency adaptation affects the synchronization properties of networks of cortical oscillators

Crook, Sharon M. and Ermentrout, G. Bard and Bower, James M. (1998) Spike frequency adaptation affects the synchronization properties of networks of cortical oscillators. Neural Computation, 10 (4). pp. 837-854. ISSN 0899-7667. http://resolver.caltech.edu/CaltechAUTHORS:CROnc98

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Abstract

Oscillations in many regions of the cortex have common temporal characteristics with dominant frequencies centered around the 40 Hz (gamma) frequency range and the 5–10 Hz (theta) frequency range. Experimental results also reveal spatially synchronous oscillations, which are stimulus dependent (Gray&Singer, 1987;Gray, König, Engel, & Singer, 1989; Engel, König, Kreiter, Schillen, & Singer, 1992). This rhythmic activity suggests that the coherence of neural populations is a crucial feature of cortical dynamics (Gray, 1994). Using both simulations and a theoretical coupled oscillator approach, we demonstrate that the spike frequency adaptation seen in many pyramidal cells plays a subtle but important role in the dynamics of cortical networks. Without adaptation, excitatory connections among model pyramidal cells are desynchronizing. However, the slow processes associated with adaptation encourage stable synchronous behavior.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1162/089976698300017511DOIUNSPECIFIED
http://www.mitpressjournals.org/doi/abs/10.1162/089976698300017511PublisherUNSPECIFIED
Additional Information:© 1998 Massachusetts Institute of Technology. Received June 9, 1997; accepted October 2, 1997. This work was supported by the NIH and NIMH. We thank J. Rinzel, A. Sherman, and P. Latham for helpful discussion and comments. The reduced pyramidal cell model is available via ftp://www.nervana.montana.edu/pub/users/crook/pyr.ode.
Funders:
Funding AgencyGrant Number
National Institutes of HealthUNSPECIFIED
National Institute of Mental HealthUNSPECIFIED
Subject Keywords:HIPPOCAMPAL PYRAMIDAL CELLS; COUPLED NEURAL OSCILLATORS; RAT PIRIFORM CORTEX; CAT VISUAL-CORTEX; COMPUTER-SIMULATION; POPULATION EVENTS; NEURONS IN-VITRO; OLFACTORY-BULB; MODULATION; ACTIVATION
Record Number:CaltechAUTHORS:CROnc98
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:CROnc98
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13262
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:06 Feb 2009 05:24
Last Modified:26 Dec 2012 10:47

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