Forster, Robert and Wilke, Claus O. (2005) Tradeoff between short-term and long-term adaptation in a changing environment. Physical Review E, 72 (4). Art. no. 041922. ISSN 1539-3755 http://resolver.caltech.edu/CaltechAUTHORS:FORpre05
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We investigate the competition dynamics of two microbial or viral strains that live in an environment that switches periodically between two states. One of the strains is adapted to the long-term environment, but pays a short-term cost, while the other is adapted to the short-term environment and pays a cost in the long term. We explore the tradeoff between these alternative strategies in extensive numerical simulations and present a simple analytic model that can predict the outcome of these competitions as a function of the mutation rate and the time scale of the environmental changes. Our model is relevant for arboviruses, which alternate between different host species on a regular basis.
|Additional Information:||©2005 The American Physical Society (Received 16 December 2004; revised 15 July 2005; published 20 October 2005) This work was supported by NIH Grant NO. AI 065960.|
|Subject Keywords:||microorganisms; evolution (biological)|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Archive Administrator|
|Deposited On:||11 Jan 2006|
|Last Modified:||26 Dec 2012 08:43|
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