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Tradeoff between short-term and long-term adaptation in a changing environment

Forster, Robert and Wilke, Claus O. (2005) Tradeoff between short-term and long-term adaptation in a changing environment. Physical Review E, 72 (4). Art. no. 041922. ISSN 1539-3755. http://resolver.caltech.edu/CaltechAUTHORS:FORpre05

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Abstract

We investigate the competition dynamics of two microbial or viral strains that live in an environment that switches periodically between two states. One of the strains is adapted to the long-term environment, but pays a short-term cost, while the other is adapted to the short-term environment and pays a cost in the long term. We explore the tradeoff between these alternative strategies in extensive numerical simulations and present a simple analytic model that can predict the outcome of these competitions as a function of the mutation rate and the time scale of the environmental changes. Our model is relevant for arboviruses, which alternate between different host species on a regular basis.


Item Type:Article
Additional Information:©2005 The American Physical Society (Received 16 December 2004; revised 15 July 2005; published 20 October 2005) This work was supported by NIH Grant NO. AI 065960.
Subject Keywords:microorganisms; evolution (biological)
Record Number:CaltechAUTHORS:FORpre05
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:FORpre05
Alternative URL:http://dx.doi.org/10.1103/PhysRevE.72.041922
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:1336
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:11 Jan 2006
Last Modified:26 Dec 2012 08:43

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