Sommer, Tobias and Peters, Jan and Gläscher, Jan and Büchel, Christian (2009) Structure–function relationships in the processing of regret in the orbitofrontal cortex. Brain Structure and Function, 213 (6). pp. 535-551. ISSN 1863-2661 http://resolver.caltech.edu/CaltechAUTHORS:20091022-151828255
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The influence of counterfactual thinking and regret on choice behavior has been widely acknowledged in economic science (Bell in Oper Res 30:961–981, 1982; Kahneman and Tversky in Judgment under uncertainty: heuristics and biases. Cambridge University Press, Cambridge, pp 201–210, 1982; Loomes and Sugden in Econ J 92:805–824, 1982). Neuroimaging studies have only recently begun to explore the neural correlates of this psychological factor and orbitofrontal cortex (OFC) activity was observed in several of them depending of the exact characteristics of the employed paradigm. This selective OFC involvement and, moreover, a consistently found dissociation of medial and lateral OFC activity clusters allow inferences to the function of this structure in counterfactual thinking and regret. Vice versa, the differential contribution of OFC subregions to these processes also adds evidence to the current debate on the function of this cortical structure in decision-making that attracted increasing attention in recent years.
|Additional Information:||© 2009 Springer. Received: 25 February 2009 Accepted: 3 September 2009 Published online: 16 September 2009. We would like to thank Xun Liu for providing the behavioral data for the reanalysis. This work was supported by the BMBF "National Network Computational Neuroscience–Bernstein Focus: Neuronal Basis of Learning".|
|Subject Keywords:||Orbitofrontal cortex (OFC); Medial OFC; Lateral OFC; Regret; Decision-making; Counterfactual thinking|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Jason Perez|
|Deposited On:||22 Oct 2009 22:45|
|Last Modified:||26 Dec 2012 11:30|
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