Cleveland, Robin O. and Bailey, Michael R. and Fineberg, Naomi and Hartenbaum, Bruce and Lokhandwalla, Murtuza and McAteer, James A. and Sturtevant, Bradford (2000) Design and characterization of a research electrohydraulic lithotripter patterned after the Dornier HM3. Review of Scientific Instruments, 71 (6). pp. 2514-2525. ISSN 0034-6748 http://resolver.caltech.edu/CaltechAUTHORS:CLErsi00
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An electrohydraulic lithotripter has been designed that mimics the behavior of the Dornier HM3 extracorporeal shock wave lithotripter. The key mechanical and electrical properties of a clinical HM3 were measured and a design implemented to replicate these parameters. Three research lithotripters have been constructed on this design and are being used in a multi-institutional, multidisciplinary research program to determine the physical mechanisms of stone fragmentation and tissue damage in shock wave lithotripsy. The acoustic fields of the three research lithotripters and of two clinical Dornier HM3 lithotripters were measured with a PVDF membrane hydrophone. The peak positive pressure, peak negative pressure, pulse duration, and shock rise time of the focal waveforms were compared. Peak positive pressures varied from 25 MPa at a voltage setting of 12 kV to 40 MPa at 24 kV. The magnitude of the peak negative pressure varied from -7 to -12 MPa over the same voltage range. The spatial variations of the peak positive pressure and peak negative pressure were also compared. The focal region, as defined by the full width half maximum of the peak positive pressure, was 60 mm long in the axial direction and 10 mm wide in the lateral direction. The performance of the research lithotripters was found to be consistent at clinical firing rates (up to 3 Hz). The results indicated that pressure fields in the research lithotripters are equivalent to those generated by a clinical HM3 lithotripter.
|Additional Information:||Copyright © 2000 American Institute of Physics. Received 23 November 1999; accepted 15 February 2000. This work was funded by the National Institutes of Health through Grant No. DK43881. The authors thank Dr. George Keilman and Dr. O. A. Sapozhnikov for technical assistance and Dr. J. E. Lingeman and Dr. A. P. Evan for providing access to the HM3 lithotripters at Methodist Hospital.|
|Subject Keywords:||kidney; biomedical ultrasonics; radiation therapy; acoustic field; sparks; ultrasonic focusing; biomedical equipment|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||13 Feb 2006|
|Last Modified:||26 Dec 2012 08:45|
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