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WormBase: a comprehensive resource for nematode research

Harris, Todd W. and Antoshechkin, Igor and Bieri, Tamberlyn and Blasiar, Darin and Chan, Juancarlos and Chen, Wen J. and De La Cruz, Norie and Davis, Paul and Duesbury, Margaret and Fang, Ruihua and Fernandes, Jolene and Han, Michael and Kishore, Ranjana and Lee, Raymond and Müller, Hans-Michael and Nakamura, Cecilia and Ozersky, Philip and Petcherski, Andrei and Rangarajan, Arun and Rogers, Anthony and Schindelman, Gary and Schwarz, Erich M. and Tuli, Mary Ann and Van Auken, Kimberly and Wang, Daniel and Wang, Xiaodong and Williams, Gary and Yook, Karen and Durbin, Richard and Stein, Lincoln D. and Spieth, John and Sternberg, Paul W. (2010) WormBase: a comprehensive resource for nematode research. Nucleic Acids Research, 38 (D1). D463-D467. ISSN 0305-1048 http://resolver.caltech.edu/CaltechAUTHORS:20100527-134537612

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Abstract

WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.


Item Type:Article
Additional Information:© The Author(s) 2009. Published by Oxford University Press. Received September 15, 2009; Revised October 11, 2009; Accepted October 12, 2009. US National Institutes of Health (Grant no. P41 HG02223); US National Human Genome Research Institute (Grant no. P41-HG02223 to WormBase); British Medical Research Council (to WormBase); P.W.S. is an investigator with the Howard Hughes Medical Institute. Funding for open access charge: US National Human Genome Research Institute (Grant P41-HG02223).
Funders:
Funding AgencyGrant Number
NIHP41HG02223
US National Human Genome Research InstituteP41-HG02223
British Medical Research CouncilUNSPECIFIED
Howard Hughes Medical InstituteUNSPECIFIED
Record Number:CaltechAUTHORS:20100527-134537612
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20100527-134537612
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Official Citation:WormBase: a comprehensive resource for nematode research Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri, Darin Blasiar, Juancarlos Chan, Wen J. Chen, Norie De La Cruz, Paul Davis, Margaret Duesbury, Ruihua Fang, Jolene Fernandes, Michael Han, Ranjana Kishore, Raymond Lee, Hans-Michael Müller, Cecilia Nakamura, Philip Ozersky, Andrei Petcherski, Arun Rangarajan, Anthony Rogers, Gary Schindelman, Erich M. Schwarz, Mary Ann Tuli, Kimberly Van Auken, Daniel Wang, Xiaodong Wang, Gary Williams, Karen Yook, Richard Durbin, Lincoln D. Stein, John Spieth, and Paul W. Sternberg
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:18482
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:24 Jun 2010 21:28
Last Modified:26 Dec 2012 12:05

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