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Three-Dimensional Structure and Thermal Stability Studies of DNA Nanostructures by Energy Transfer Spectroscopy

Lee, Jong Bum and Shai, Adam S. and Campolongo, Michael J. and Park, Nokyoung and Luo, Dan (2010) Three-Dimensional Structure and Thermal Stability Studies of DNA Nanostructures by Energy Transfer Spectroscopy. ChemPhysChem, 11 (10). pp. 2081-2084. ISSN 1439-4235 http://resolver.caltech.edu/CaltechAUTHORS:20100817-091631784

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Abstract

Structural changes and stability of DNA nanoarchitectures including Y-shaped DNA (see picture), dendrimer-like DNA, and DNA hydrogels are investigated. The results demonstrate the feasibility and flexibility of FRET and NSET (Förster resonance/ nanometal surface- energy transfer) in determining difficult-to-obtain 3D structures and characterizing the thermal responses of DNA nanoarchitectures in real time.


Item Type:Article
Additional Information:© 2010 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim. Article first published online: 5 May 2010. This work was partially supported by the USDA NRI and the NSF CAREER award, and performed in part at the Nanobiotechnology Center and Cornell Center for Materials Research, which are supported by the National Science Foundation, Cornell University, and industrial affiliates.
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Funding AgencyGrant Number
U.S. Department of Agriculture National Research Initiative (USDA NRI)UNSPECIFIED
NSFUNSPECIFIED
Cornell University UNSPECIFIED
Subject Keywords:DNA; DNA structures; FRET; hydrogels; nanometal surface energy transfer
Record Number:CaltechAUTHORS:20100817-091631784
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20100817-091631784
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ID Code:19467
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:17 Aug 2010 18:11
Last Modified:26 Dec 2012 12:19

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