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Fabrication of biomolecule–copolymer hybrid nanovesicles as energy conversion systems

Ho, Dean and Chu, Benjamin and Lee, Hyeseung and Brooks, Evan K. and Kuo, Karen and Montemagno, Carlo D. (2005) Fabrication of biomolecule–copolymer hybrid nanovesicles as energy conversion systems. Nanotechnology, 16 (12). pp. 3120-3132. ISSN 0957-4484. http://resolver.caltech.edu/CaltechAUTHORS:HODnano05

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Abstract

This work demonstrates the integration of the energy-transducing proteins bacteriorhodopsin (BR) from Halobacterium halobium and cytochrome c oxidase (COX) from Rhodobacter sphaeroides into block copolymeric vesicles towards the demonstration of coupled protein functionality. An ABA triblock copolymer-based biomimetic membrane possessing UV-curable acrylate endgroups was synthesized to serve as a robust matrix for protein reconstitution. BR-functionalized polymers were shown to generate light-driven transmembrane pH gradients while pH gradient-induced electron release was observed from COX-functionalized polymers. Cooperative behaviour observed from composite membrane functionalized by both proteins revealed the generation of microamp-range currents with no applied voltage. As such, it has been shown that the fruition of technologies based upon bio-functionalizing abiotic materials may contribute to the realization of high power density devices inspired by nature.


Item Type:Article
Additional Information:© Institute of Physics 2005 Received 10 May 2005, in final form 8 September 2005, Published 11 November 2005, Print publication: Issue 12 (December 2005) This work was supported by DARPA grant N66001-02-C-8402. The authors gratefully acknowledge the Ferguson-Miller group for the engineered COX strains. The authors would also like the thank Mr Hyo-Jick Choi for TEM assistance.
Record Number:CaltechAUTHORS:HODnano05
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:HODnano05
Alternative URL:http://dx.doi.org/10.1088/0957-4484/16/12/066
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:2028
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:02 Mar 2006
Last Modified:26 Dec 2012 08:47

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