Frei, Mark G. and Zaveri, Hitten P. and Arthurs, Susan and Bergey, Gregory K. and Jouny, Christophe C. and Lehnertz, Klaus and Gotman, Jean and Osorio, Ivan and Netoff, Theoden I. and Freeman, Walter J. and Jefferys, John and Worrell, Gregory and Le Van Quyen, Michel and Schiff, Steven J. and Mormann, Florian (2010) Controversies in epilepsy: Debates held during the Fourth International Workshop on Seizure Prediction. Epilepsy and Behavior, 19 (1). pp. 4-16. ISSN 1525-5050 http://resolver.caltech.edu/CaltechAUTHORS:20101027-084403611
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Debates on six controversial topics were held during the Fourth International Workshop on Seizure Prediction (IWSP4) convened in Kansas City, KS, USA, July 4–7, 2009. The topics were (1) Ictogenesis: Focus versus Network? (2) Spikes and Seizures: Step-relatives or Siblings? (3) Ictogenesis: A Result of Hyposynchrony? (4) Can Focal Seizures Be Caused by Excessive Inhibition? (5) Do High-Frequency Oscillations Provide Relevant Independent Information? (6) Phase Synchronization: Is It Worthwhile as Measured? This article, written by the IWSP4 organizing committee and the debaters, summarizes the arguments presented during the debates.
|Additional Information:||© 2010 Elsevier. Received 9 June 2010; accepted 9 June 2010. Available online 13 August 2010. Funding for IWSP4 was received from the following foundations, government agencies, industries, university and hospital partners, and individuals: Alliance for Epilepsy Research, UCB, Cyberonics, Deutsche Gesellschaft für Epileptologie, NeuroVista, American Epilepsy Society, CURE, University of Kansas Medical Center, Children's Mercy Hospitals and Clinics, Honeywell—Kansas City Plant, Ad-Tech, Cardinal Health, Medtronic, DIXI, Boulevard Brewing Company, and Mary Shaw Branton, Don Alexander, and Frank and Helen Wewers. Funding was also made possible in part by Grant R13NS065535 from the National Institute of Neurological Disorders and Stroke (NINDS), Office of Rare Disease Research (ORDR), and National Institute of Child Health and Human Development (NICHD). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily represent the official views of the NINDS, ORDR, NICHD, or National Institutes of Health (NIH) and do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.|
|Subject Keywords:||Seizure focus; Seizure onset area; Network; Interictal activity; Spikes; Ictogenesis; Inhibition; Excitation; Hyposynchrony; Hypersynchrony; High-frequency activity; High-frequency oscillations; Phase synchronization|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||15 Nov 2010 20:42|
|Last Modified:||26 Dec 2012 12:33|
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