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Computational protein design

Street, Arthur G. and Mayo, Stephen L. (1999) Computational protein design. Structure, 7 (5). R105-R109. ISSN 0969-2126.

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A 'protein design cycle', involving cycling between theory and experiment, has led to recent advances in rational protein design. A reductionist approach, in which protein positions are classified by their local environments, has aided development of an appropriate energy expression. The computational principles and practicalities of the protein design cycle are discussed.

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Additional Information:© 1999 Elsevier Science Ltd. Available online 6 July 1999.
Subject Keywords:Protein Conformation, Proteins, Algorithms
Record Number:CaltechAUTHORS:20110620-160435008
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Official Citation:Arthur G Street, Stephen L Mayo, Computational protein design, Structure, Volume 7, Issue 5, 15 May 1999, Pages R105-R109, ISSN 0969-2126, DOI: 10.1016/S0969-2126(99)80062-8. (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:24131
Deposited By: Marie Ary
Deposited On:21 Jun 2011 22:11
Last Modified:21 Jun 2011 22:12

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