Vermesh, Udi and Vermesh, Ophir and Wang, Jun and Kwong, Gabriel A. and Ma, Chao and Hwang, Kiwook and Heath, James R. (2011) High-Density, Multiplexed Patterning of Cells at Single-Cell Resolution for Tissue Engineering and Other Applications. Angewandte Chemie International Edition, 50 (32). pp. 7378-7380. ISSN 1433-7851 http://resolver.caltech.edu/CaltechAUTHORS:20110706-095329536
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Abstract
Surface chemistry meets tissue engineering: A novel surface-patterning approach for creating arrays of DNA squares is combined with a unique method for DNA-encoding of cells to construct dense arrays of distinct single cells. The cell patterns can be transferred from the substrate surface into thin hydrogel films, and these layers can be stacked to form 3D tissue constructs.
| Item Type: | Article | ||||||||
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| Additional Information: | © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: March 31, 2011. Published online: June 29, 2011. This work was funded by the National Cancer Institute Grant No. 5U54 CA119347 (JRH PI) and by generous support from the Ivy Foundation and the Grand Duchy of Luxembourg, via a subcontract from the Institute for Systems Biology. We thank Integrated Sensing Systems, Inc. for help with silicon hard mold fabrication and M. Di Franco for technical assistance. | ||||||||
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| Subject Keywords: | cell assembly; flow-patterning; microarrays; microfluidics; tissue engineering | ||||||||
| Record Number: | CaltechAUTHORS:20110706-095329536 | ||||||||
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:20110706-095329536 | ||||||||
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| Official Citation: | Vermesh, U., Vermesh, O., Wang, J., Kwong, G. A., Ma, C., Hwang, K. and Heath, J. R. (2011), High-Density, Multiplexed Patterning of Cells at Single-Cell Resolution for Tissue Engineering and Other Applications. Angewandte Chemie International Edition, 50: 7378–7380. doi: 10.1002/anie.201102249 | ||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 24313 | ||||||||
| Collection: | CaltechAUTHORS | ||||||||
| Deposited By: | Jason Perez | ||||||||
| Deposited On: | 05 Aug 2011 18:50 | ||||||||
| Last Modified: | 05 Aug 2011 18:50 |
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