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Optofluidic microscopy

Heng, Xin and Erickson, David and Psaltis, Demetri and Yang, Changhuei (2005) Optofluidic microscopy. In: 2005 Proceedings of the 3rd International Conference on Microchannels and Minichannels. American Society of Mechanical Engineers , New York, pp. 569-574. ISBN 0-7918-4185-5 http://resolver.caltech.edu/CaltechAUTHORS:20110812-143350079

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Abstract

Recent advances in the development of lab-on-a-chip devices have been rapid and broad ranging. In general however these devices, while containing micro- or even nano-scale components, rely heavily on macroscale infrastructure (e.g. microscopes, chip readers and power sources) to perform much of the actual product detection and subsequent analysis. As such to enable the next generation of portable lab-on-chip devices, techniques for simply and cheaply integrating on-chip analysis functionalities will be required. In this work we present our work directed towards the development of a new concept in rapid on-chip imaging which we refer to as "optofluidic microscopy (OFM)". Here we present an overview of the imaging theory, fabrication procedure and operational details of the initial prototype. Preliminary experimental results of this on-chip optical imager are also reported. A significant advantage of the technique is that through proper spatial scaling, sub-wavelength resolution can be achieved without bulk optics.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1115/ICMM2005-75206DOIUNSPECIFIED
Additional Information:© 2005 ASME. This work was carried out under the funding support from the DARPA center for optofluidic integration. We thank the Caltech Watson clean room facility for the access of the micro-fabrication utility.
Funders:
Funding AgencyGrant Number
DARPA Center for Optofluidic IntegrationUNSPECIFIED
Record Number:CaltechAUTHORS:20110812-143350079
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20110812-143350079
Official Citation:Optofluidic Microscopy Xin Heng, David Erickson, Demetri Psaltis, and Changhuei Yang, ASME Conf. Proc. 2005, 569 (2005), DOI:10.1115/ICMM2005-75206
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:24836
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:13 Sep 2011 18:14
Last Modified:08 Dec 2014 20:42

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