Wagenaar, Daniel A. and Potter, Steve M. (2004) A versatile all-channel stimulator for electrode arrays, with real-time control. Journal of Neural Engineering, 1 (1). pp. 39-45. ISSN 1741-2560 http://resolver.caltech.edu/CaltechAUTHORS:20110907-093554097
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Over the last few decades, technology to record through ever increasing numbers of electrodes has become available to electrophysiologists. For the study of distributed neural processing, however, the ability to stimulate through equal numbers of electrodes, and thus to attain bidirectional communication, is of paramount importance. Here, we present a stimulation system for multi-electrode arrays which interfaces with existing commercial recording hardware, and allows stimulation through any electrode in the array, with rapid switching between channels. The system is controlled through real-time Linux, making it extremely flexible: stimulation sequences can be constructed on-the-fly, and arbitrary stimulus waveforms can be used if desired. A key feature of this design is that it can be readily and inexpensively reproduced in other labs, since it interfaces to standard PC parallel ports and uses only off-the-shelf components. Moreover, adaptation for use with in vivo multi-electrode probes would be straightforward. In combination with our freely available data-acquisition software, MeaBench, this system can provide feedback stimulation in response to recorded action potentials within 15 ms.
|Additional Information:||© 2004 IOP Publishing Ltd. Received 19 January 2004; Accepted for publication 19 February 2004; Published 15 March 2004. This work was partially supported by grants NS044134 and NS38628 from NIH/NINDS, and EB000786 from NIH/NIBIB, and by the Whitaker Foundation and the NSF Center for Behavioral Neuroscience. We thank Jerry Pine and Thomas DeMarse for useful conversations about many design issues.|
|Classification Code:||PACS: 87.63.-d; 87.17.-d; 87.19.R-; 87.19.L-; 87.85.Wc|
|Official Citation:||A versatile all-channel stimulator for electrode arrays, with real-time control Daniel A Wagenaar and Steve M Potter 2004 J. Neural Eng. 1 39|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||08 Sep 2011 16:47|
|Last Modified:||26 Dec 2012 13:39|
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