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Designing proteins for therapeutic applications

Lazar, Greg A. and Marshall, Shannon A. and Plecs, Joseph J. and Mayo, Stephen L. and Desjarlais, John R. (2003) Designing proteins for therapeutic applications. Current Opinion in Structural Biology, 13 (4). pp. 513-518. ISSN 0959-440X. http://resolver.caltech.edu/CaltechAUTHORS:20110913-173425194

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Abstract

Protein design is becoming an increasingly useful tool for optimizing protein drugs and creating novel biotherapeutics. Recent progress includes the engineering of monoclonal antibodies, cytokines, enzymes and viral fusion inhibitors.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S0959-440X(03)00104-0DOIUNSPECIFIED
http://www.sciencedirect.com/science/article/pii/S0959440X03001040PublisherUNSPECIFIED
Additional Information:© 2003 Elsevier Ltd. Available online 19 July 2003. This review comes from a themed issue on Engineering and design. Edited by Sophie E Jackson and Lynne Regan.
Subject Keywords:Animals; Antibodies: Monoclonal; Protein Engineering; Antiviral Agents; Proteins; Humans; Cytokines
Record Number:CaltechAUTHORS:20110913-173425194
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20110913-173425194
Official Citation:Greg A Lazar, Shannon A Marshall, Joseph J Plecs, Stephen L Mayo, John R Desjarlais, Designing proteins for therapeutic applications, Current Opinion in Structural Biology, Volume 13, Issue 4, August 2003, Pages 513-518, ISSN 0959-440X, 10.1016/S0959-440X(03)00104-0.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:25330
Collection:CaltechAUTHORS
Deposited By: Marie Ary
Deposited On:23 Sep 2011 23:07
Last Modified:23 Sep 2011 23:07

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