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Experimental and computational studies of negative near-wall shear stress in the human aorta and its correlation with various stages of CHF

Gharib, M. and Beizai, M. and Saber, N. R. (2002) Experimental and computational studies of negative near-wall shear stress in the human aorta and its correlation with various stages of CHF. In: Second Joint EMBS-BMES Conference 2002. Proceedings of Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , pp. 1254-1255. ISBN 0-7803-7612-9 http://resolver.caltech.edu/CaltechAUTHORS:20111102-095344509

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Abstract

In this article, we report our in vitro observations demonstrating that reduced blood flow combined with increased heartbeat can lead to a retrograde flow adjacent to the vessel wall and thereby high negative wall shear stress over a major part of cardiac cycle. We attempt to map the correlation between the level of retrograde flow in the descending aorta and the severity of congestive heart failure (CHF), using both experimental methods and computational fluid dynamics (CFD) simulations.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/IEMBS.2002.1106374DOIUNSPECIFIED
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=1106374PublisherUNSPECIFIED
Additional Information:© 2002 IEEE. Issue Date: 2002; Date of Current Version: 06 January 2003.
Subject Keywords:aorta; heart failure; retrograde; endothelium; computational fluid dynamics
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INSPEC Accession Number7591607
Record Number:CaltechAUTHORS:20111102-095344509
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20111102-095344509
Official Citation:Gharib, M.; Beizai, M.; Saber, N.R.; , "Experimental and computational studies of negative near-wall shear stress in the human aorta and its correlation with various stages of CHF," Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint , vol.2, no., pp. 1254- 1255 vol.2, 2002 doi: 10.1109/IEMBS.2002.1106374
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:27580
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:02 Nov 2011 17:29
Last Modified:02 Nov 2011 17:29

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