Gharib, M. and Beizai, M. and Saber, N. R. (2002) Experimental and computational studies of negative near-wall shear stress in the human aorta and its correlation with various stages of CHF. In: Second Joint EMBS-BMES Conference 2002. Proceedings of Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , pp. 1254-1255. ISBN 0-7803-7612-9 http://resolver.caltech.edu/CaltechAUTHORS:20111102-095344509
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In this article, we report our in vitro observations demonstrating that reduced blood flow combined with increased heartbeat can lead to a retrograde flow adjacent to the vessel wall and thereby high negative wall shear stress over a major part of cardiac cycle. We attempt to map the correlation between the level of retrograde flow in the descending aorta and the severity of congestive heart failure (CHF), using both experimental methods and computational fluid dynamics (CFD) simulations.
|Item Type:||Book Section|
|Additional Information:||© 2002 IEEE. Issue Date: 2002; Date of Current Version: 06 January 2003.|
|Subject Keywords:||aorta; heart failure; retrograde; endothelium; computational fluid dynamics|
|Other Numbering System:|
|Official Citation:||Gharib, M.; Beizai, M.; Saber, N.R.; , "Experimental and computational studies of negative near-wall shear stress in the human aorta and its correlation with various stages of CHF," Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint , vol.2, no., pp. 1254- 1255 vol.2, 2002 doi: 10.1109/IEMBS.2002.1106374|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Jason Perez|
|Deposited On:||02 Nov 2011 17:29|
|Last Modified:||02 Nov 2011 17:29|
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