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Identification of the Vesicular Stomatitis Virus Large Protein as a Unique Viral Protein

Stampfer, Martha and Baltimore, David (1973) Identification of the Vesicular Stomatitis Virus Large Protein as a Unique Viral Protein. Journal of Virology, 11 (4). pp. 520-526. ISSN 0022-538X. http://resolver.caltech.edu/CaltechAUTHORS:20120807-161758173

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Abstract

Previous studies have noted the existence of a 190,000-daltoin vesicular stomatitis virus (VSV) protein called the large (L) protein. To determine whether this protein is a nonspecific aggregate, a precursor to the other VSV proteins, or a unique viral protein, its synthesis relative to the other VSV proteins was studied under conditions of inhibition of initiation of protein synthesis. Also, its tryptic peptides were compared to those of the other VSV proteins. In both cases the results were consistent with the identification of the large protein as a unique viral protein.


Item Type:Article
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http://jvi.asm.org/content/11/4/520.abstractPublisherUNSPECIFIED
Additional Information:© 1973 American Society for Microbiology. Received for publication 30 November 1972. We thank Nora Meuth for technical assistance. This work was supported by a grant from the American Cancer Society. M. S. was a predoctoral fellow of the National Science Foundation, and D. B. was a Faculty Research Awardee of the American Cancer Society.
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American Cancer SocietyUNSPECIFIED
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Record Number:CaltechAUTHORS:20120807-161758173
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20120807-161758173
Official Citation:Identification of the Vesicular Stomatitis Virus Large Protein as a Unique Viral Protein Martha Stampfer and David Baltimore J. Virol. April 1973 11:520-526
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:32996
Collection:CaltechAUTHORS
Deposited By: Aucoeur Ngo
Deposited On:07 Aug 2012 23:26
Last Modified:07 Aug 2012 23:26

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