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Polymer nanoparticle-based cancer therapeutics: from concept to clinic

Davis, M. E. (2010) Polymer nanoparticle-based cancer therapeutics: from concept to clinic. In: International Chemical Congress of Pacific Basin Societies (Pacifichem 2010), December 15-20, 2010, Honolulu, HI. http://resolver.caltech.edu/CaltechAUTHORS:20120815-152834973

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Abstract

Nanoparticle-based therapeutics contg. either small mol. anti-cancer agents (IT-101; entered Phase II) or siRNA (CALAA-01; in Phase I) are described. The key component in each nanoparticle is a cyclodextrin-contg. polymer that endows it with multifunctional behavior. Relationships between nanoparticle design and function in animal models are illustrated. Results from clin. trials are presented so show how nanoparticle-based therapeutics can provide interesting behavior in humans.


Item Type:Conference or Workshop Item (Paper)
Additional Information:© 2012 American Chemical Society.
Record Number:CaltechAUTHORS:20120815-152834973
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20120815-152834973
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:33240
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:15 Aug 2012 23:04
Last Modified:15 Aug 2012 23:04

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