Davis, M. E. (2010) Polymer nanoparticle-based cancer therapeutics: from concept to clinic. In: International Chemical Congress of Pacific Basin Societies (Pacifichem 2010), December 15-20, 2010, Honolulu, HI. http://resolver.caltech.edu/CaltechAUTHORS:20120815-152834973
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Abstract
Nanoparticle-based therapeutics contg. either small mol. anti-cancer agents (IT-101; entered Phase II) or siRNA (CALAA-01; in Phase I) are described. The key component in each nanoparticle is a cyclodextrin-contg. polymer that endows it with multifunctional behavior. Relationships between nanoparticle design and function in animal models are illustrated. Results from clin. trials are presented so show how nanoparticle-based therapeutics can provide interesting behavior in humans.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Additional Information: | © 2012 American Chemical Society. |
| Record Number: | CaltechAUTHORS:20120815-152834973 |
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:20120815-152834973 |
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 33240 |
| Collection: | CaltechAUTHORS |
| Deposited By: | Tony Diaz |
| Deposited On: | 15 Aug 2012 23:04 |
| Last Modified: | 15 Aug 2012 23:04 |
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