CaltechAUTHORS
  A Caltech Library Service

Neurospora Mutant Exhibiting Hyperproduction of Amylase and Invertase

Gratzner, Howard and Sheehan, D. N. (1969) Neurospora Mutant Exhibiting Hyperproduction of Amylase and Invertase. Journal of Bacteriology, 97 (2). pp. 544-549. ISSN 0021-9193. http://resolver.caltech.edu/CaltechAUTHORS:20120816-093814786

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:20120816-093814786

Abstract

A mutant strain of Neurospora crassa has been isolated which is derepressed for amylase and β-fructofuranosidase (invertase). Large amounts of the two enzymes were secreted into the culture medium upon depletion of exogenous carbon source. The resulting increases of the two extracellular enzymes were prevented by actinomycin D, cycloheximide, and glycerol. The starving cells of the mutant strain produced amylase and invertase de novo, as evidenced by incorporation of radioactive amino acids into the enzymes. Preliminary genetic studies indicate that these elevated enzyme levels described are due to a single gene mutation.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://jb.asm.org/content/97/2/544.abstractPublisherUNSPECIFIED
Additional Information:© 1969 American Society for Microbiology. Received for publication 1 November 1968. This investigation was supported by National Science Foundation grant GB-4537 and by a special Public Health Service fellowship, IF3-CA-25,17301. We are grateful for the very able assistance of Stephen Bloom.
Funders:
Funding AgencyGrant Number
NSFGB-4537
Public Health Service fellowshipIF3-CA-25,17301
Record Number:CaltechAUTHORS:20120816-093814786
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20120816-093814786
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:33256
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:16 Aug 2012 17:39
Last Modified:16 Aug 2012 17:39

Repository Staff Only: item control page