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Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

Ahn, Andrew and Yang, Changhuei and Wax, Adam and Popescu, Gabriel and Fang-Yen, Christopher and Badizadegan, Kamran and Dasari, Ramachandra R. and Feld, Michael S. (2005) Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer. Applied Optics, 44 (7). pp. 1188-1190. ISSN 0003-6935. http://resolver.caltech.edu/CaltechAUTHORS:AHNao05

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Abstract

Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.


Item Type:Article
Additional Information:© 2005 Optical Society of America Received 3 June 2004; revised manuscript received 20 October 2004; accepted 20 October 2004. This research was supported by the National Institutes of Health grant P41-RR02594-18 and by the Hamamatsu Corporation.
Subject Keywords:Medical and biological imaging; Interferometry
Record Number:CaltechAUTHORS:AHNao05
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:AHNao05
Alternative URL:http://www.opticsinfobase.org/abstract.cfm?URI=ao-44-7-1188
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:3339
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:31 May 2006
Last Modified:08 Dec 2014 23:23

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