Morita, Hiromichi and Shiraishi, Akio (1968) Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides. Journal of General Physiology, 52 (4). pp. 559-583. ISSN 0022-1295 http://resolver.caltech.edu/CaltechAUTHORS:20120831-102034973
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Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not completely differentiated for glucose and for fructose combination, (b) that the receptor site is composed of two subunits. Such suggestions are based on the classical model, where the response is proportional to the number of the sites, two subunits of each site being simultaneously occupied with one molecule of disaccharides or two molecules of monosaccharides. It is shown, however, that an allosteric model gives a somewhat better interpretation of the experimental results.
|Additional Information:||© 1968 Rockefeller University Press. Submitted April 15, 1968; Published October 1, 1968. This work was supported in part by the Scientific Research Fund from the Ministry of Education of Japan and under the sponsorship of the United States Army Research and Development Group (Far East), Department of the Army, DA-CRD-AG-S92-544-67-G61. The contents of this paper fulfill in part the requirement for the Doctoral Thesis of one of us (A.S.) at Kyushu University.|
|Official Citation:||Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides Hiromichi Morita and Akio Shiraishi J Gen Physiol 1968 52:559-583. Published October 1, 1968, doi:10.1085/jgp.52.4.559|
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|Deposited By:||Aucoeur Ngo|
|Deposited On:||31 Aug 2012 17:51|
|Last Modified:||26 Dec 2012 16:05|
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