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Restriction endonuclease cleavage maps of rat and mouse mitochondrial DNAs

Parker, Richard C. and Watson, Robert M. (1977) Restriction endonuclease cleavage maps of rat and mouse mitochondrial DNAs. Nucleic Acids Research, 4 (5). pp. 1291-1299. ISSN 0305-1048. http://resolver.caltech.edu/CaltechAUTHORS:PARnar77

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Abstract

Mitochondrial DNA from an Old World mouse, Mus musculus, and from an Old World rat, Rattus norvegicus, contain 19 and 22 distinct sites, respectively, for the 8 restriction encfonucleases, BamHI, EcoRI, HaeII, HhaI, HincII, HindIII, HpaI and PstI. The relative positions of the sites have been mapped by the study of partial and double enzyme digests. Some sites may have been conserved between the mouse and rat mitochondrial genomes.


Item Type:Article
Additional Information:Copyright © 1977 Oxford University Press. Received February 28, 1977. We wish to express our appreciation to K. Moore, P. Johnson, S. Chandler, and L. Grossman for informing us of their preliminary mouse mtDNA mapping results. We thank S. Conrad, M. Klymkowsky, and A. Sodja for their invaluable assistance, L. Matsumoto for his electron microscopy results that confirmed the HaeII site on mouse mtDNA, and Professors J. Strauss and N. Davidson for helpful discussions. This work was supported in part by USPHS NIH Grants GM 15327 and CA 08014. This is contribution no. 5525 from the Division of Chemistry and Chemical Engineering. This work was done in Jerry Vinograd's laboratory after his unfortunate death. His leadership and the standards he set made it possible. We dedicate this paper to him.
Record Number:CaltechAUTHORS:PARnar77
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:PARnar77
Alternative URL:http://nar.oxfordjournals.org/cgi/content/abstract/4/5/1291
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:4019
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:24 Jul 2006
Last Modified:26 Dec 2012 08:57

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