Koch, Christof and Segev, Idan (2000) The role of single neurons in information processing. Nature Neuroscience, 3 (11s). pp. 1171-1177. ISSN 1097-6256. http://resolver.caltech.edu/CaltechAUTHORS:20130816-103250693
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Neurons carry out the many operations that extract meaningful information from sensory receptor arrays at the organism’s periphery and translate these into action, imagery and memory. Within today’s dominant computational paradigm, these operations, involving synapses, membrane ionic channels and changes in membrane potential, are thought of as steps in an algorithm or as computations. The role of neurons in these computations has evolved conceptually from that of a simple integrator of synaptic inputs until a threshold is reached and an output pulse is initiated, to a much more sophisticated processor with mixed analog-digital logic and highly adaptive synaptic elements.
|Additional Information:||© 2000 Nature America Inc. Received 7 June; Accepted 29 September 2000. Work in the laboratories of the authors is supported by the NSF/ERC program, NIMH, ONR, Israeli Science Foundation and the BSF. We thank R. Nitzan for Fig. 2a, Y. Manor for Fig. 2b, J. Andersen for the two pyramidal cells in Fig. 2c and d, M. Rapp for Fig. 2e, B. Burke for Fig. 2f, M. Larkum for Fig. 3, F. Gabbiani for Fig. 4 and F. Gabbiani and G. Kreiman for comments.|
|Group:||Koch Laboratory, KLAB|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||KLAB Import|
|Deposited On:||16 Jan 2008 01:07|
|Last Modified:||25 Mar 2015 22:19|
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