Jacobs, Bob and Creswell, Johanna and Britt, Jonathan P. and Ford, Kevin L. and Bogen, Joseph E. and Zaidel, Eran (2003) Quantitative analysis of cortical pyramidal neurons after corpus callosotomy. Annals of Neurology, 54 (1). pp. 126-30. ISSN 0364-5134. http://resolver.caltech.edu/CaltechAUTHORS:20130816-103258429
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This study quantitatively explored the dendritic/spine extent of supragranular pyramidal neurons across several cortical areas in two adult male subjects who had undergone a callosotomy several decades before death. In all cortical areas, there were numerous atypical, supragranular pyramidal neurons with elongated “tap root” basilar dendrites. These atypical cells could be associated with an underlying epileptic condition and/or could represent a compensatory mechanism in response to deafferentation after callosotomy.
|Additional Information:||Issue published online: 25 JUN 2003, Article first published online: 30 MAY 2003, Manuscript Accepted: 1 APR 2003, Manuscript Revised: 25 MAR 2003, Manuscript Received: 13 AUG 2002. © 2003 American Neurological Association Published by Wiley-Liss, Inc., through Wiley Subscription Services. This work was supported by the National Science Foundation’s Division of Undergraduate Education grant (DUE-9550790, B.J.), the Hughes Foundation, and Colorado College’s divisional research funds. We thank M. Hrubes for her contributions to this project.|
|Group:||Koch Laboratory, KLAB|
|Official Citation:||Jacobs, B., Creswell, J., Britt, J. P., Ford, K. L., Bogen, J. E. and Zaidel, E. (2003), Quantitative analysis of cortical pyramidal neurons after corpus callosotomy. Ann Neurol., 54: 126–130. doi: 10.1002/ana.10620|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||KLAB Import|
|Deposited On:||16 Jan 2008 02:21|
|Last Modified:||02 Oct 2013 18:33|
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