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Quantitative analysis of cortical pyramidal neurons after corpus callosotomy.

Jacobs, Bob and Creswell, Johanna and Britt, Jonathan P. and Ford, Kevin L. and Bogen, Joseph E. and Zaidel, Eran (2003) Quantitative analysis of cortical pyramidal neurons after corpus callosotomy. Annals of Neurology, 54 (1). pp. 126-30. ISSN 0364-5134. http://resolver.caltech.edu/CaltechAUTHORS:20130816-103258429

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Abstract

This study quantitatively explored the dendritic/spine extent of supragranular pyramidal neurons across several cortical areas in two adult male subjects who had undergone a callosotomy several decades before death. In all cortical areas, there were numerous atypical, supragranular pyramidal neurons with elongated “tap root” basilar dendrites. These atypical cells could be associated with an underlying epileptic condition and/or could represent a compensatory mechanism in response to deafferentation after callosotomy.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1002/ana.10620DOIArticle
http://onlinelibrary.wiley.com/doi/10.1002/ana.10620/abstractPublisherArticle
Additional Information:Issue published online: 25 JUN 2003, Article first published online: 30 MAY 2003, Manuscript Accepted: 1 APR 2003, Manuscript Revised: 25 MAR 2003, Manuscript Received: 13 AUG 2002. © 2003 American Neurological Association Published by Wiley-Liss, Inc., through Wiley Subscription Services. This work was supported by the National Science Foundation’s Division of Undergraduate Education grant (DUE-9550790, B.J.), the Hughes Foundation, and Colorado College’s divisional research funds. We thank M. Hrubes for her contributions to this project.
Group:Koch Laboratory, KLAB
Funders:
Funding AgencyGrant Number
NSF Division of Undergraduate EducationDUE-9550790
Hughes FoundationUNSPECIFIED
Colorado CollegeUNSPECIFIED
Record Number:CaltechAUTHORS:20130816-103258429
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20130816-103258429
Official Citation:Jacobs, B., Creswell, J., Britt, J. P., Ford, K. L., Bogen, J. E. and Zaidel, E. (2003), Quantitative analysis of cortical pyramidal neurons after corpus callosotomy. Ann Neurol., 54: 126–130. doi: 10.1002/ana.10620
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:40598
Collection:CaltechAUTHORS
Deposited By: KLAB Import
Deposited On:16 Jan 2008 02:21
Last Modified:02 Oct 2013 18:33

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