Mormann, Florian and Fernández, Guillén and Klaver, Peter and Weber, Bernd and Elger, Christian E. and Fell, Juergen (2007) Declarative memory formation in hippocampal sclerosis: an intracranial event-related potentials study. NeuroReport, 18 (4). pp. 317-321. ISSN 0959-4965. http://resolver.caltech.edu/CaltechAUTHORS:20130816-103303631
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The functional deficits associated with hippocampal sclerosis during declarative memory formation are largely unknown. In this study, we analyzed intracranial event-related potentials recorded from the medial temporal lobes of nine epilepsy patents performing a word memorization task. We used frequency-specific wavelet analysis to assess stimulus-related changes in power and intertrial phase coherence. Statistical analysis revealed a significan decrease of stimulus-induced power in the d and y range on the side of pathology. No significant differences in phase locking were observed. Findings indicate a reduced availability of recruitable neural assemblies not only in the hippocampus but also in the rhinal cortex during memory formation. Network functions related to the timing of neural responses to the stimulus appear to be preserved.
|Additional Information:||© 2007 Lippincott Williams & Wilkins, Inc. Received 21 November 2006; accepted 1 December 2006.|
|Group:||Koch Laboratory, KLAB|
|Subject Keywords:||declarative memory, epilepsy, event-related potentials, hippocampal sclerosis, intracranial electroencephalogram|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||KLAB Import|
|Deposited On:||26 Jan 2008 02:10|
|Last Modified:||08 Feb 2017 17:19|
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