Benham, Craig J. (1977) Elastic Model of Supercoiling. Proceedings of the National Academy of Sciences of the United States of America, 74 (6). pp. 2397-2401. ISSN 0027-8424 http://resolver.caltech.edu/CaltechAUTHORS:BENpnas77
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An elastic model for the supercoiling of duplex DNA is developed. The simplest assumptions regarding the elastic properties of double-helical DNA (homogeneous, isotropic, of circular cross section, and remaining straight when unstressed) will generate two orders of superhelicity when stressed. Recent experimental results [Brady, G. W., Fein, D. B. & Brumberger, H. (1976) Nature 264, 231-234] suggest that in supercoiled DNA molecules there are regions where two distinct orders of supercoiling arise, as predicted by this model.
|Additional Information:||Copyright © 1977 by the National Academy of Sciences Communicated by Max Delbrück, March 25, 1977 The costs of publication of this article were defrayed in part by the payment of page charges from funds made available to support the research which is the subject of the article. This article must therefore be hereby marked "advertisement" in accordance with 18 U. S. C. §1734 solely to indicate this fact.|
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|Deposited On:||05 Oct 2006|
|Last Modified:||26 Dec 2012 09:04|
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