Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Sukhodolets, V. V.

Year :

1995

Title :

Natural-Selection in the Context of the Vertical Evolution Theory

Journal :

Genetika

Volume :

31

Issue :

1

Pages :

5-14

Date :

Jan

Short Title :

Natural-Selection in the Context of the Vertical Evolution Theory

Alternate Journal :

Genetika

Custom 2 :

ISI:A1995QF94400001

Abstract :

In modern organisms, selection operates only on the minor genes responsible for the ecological potential of an organism. Structural genes and, especially, their regions corresponding to active protein centers are conservative; hence, mutations of regulatory genes or regulatory regions of structural genes become selectively advantageous. The prevailing selection type is a regulatory, or stabilizing one, which results in the optimal performance of regulatory systems. In the process of vertical evolution, regulatory selection eliminates the negative effects of the hybridization and negative pleiotropic effect of regulatory mutations that are favored by directional selection. The concept of regulatory selection is an alternative to the neutral theory. The relationship between the ecological potential of an organism and its fitness is shown using an arbitrary geometric model. For a given genome size, the fitness of an organism is inversely proportional to its ecological potential, and vice versa. An increase in fitness is achieved directly by directional selection, while an extension of ecological potential can be caused only by the combined effects of selection and combinative recombination, or hybridization.

Notes :

Times Cited: 1 QF944 GENETIKA
 -- contributed by John Beatty, March 29, 2002