|
SCHEDULE
All meetings will held in 210 Marine Resources Center, unless
otherwise noted.
Wednesday May 19th
5:00-6:00pm Organizers and Instructors Meeting in Swope Hall
6:30-8:30 pm Opening Reception and Dinner in Swope Hall
Thursday May 20th
8:30 am “Opening Comments”
“Introduction to MBL” – Jane Maienschein
9-12 Perspectives on Molecular Evolution: An Historical
Overview
Mike Dietrich
Reading:
* Thomas Jukes, “Early Development of the Neutral
Theory,” Perspectives in Biology and Medicine 14 (1991)
473-485.
* Morris Goodman, “Epilogue: A Personal Account of
the Origins of a New Paradigm,” Molecular Phylogenetics
and Evolution 5 (1996) 269-285.
* R. F. Doolittle, “Some reflections on the early
days of sequence searching,” Journal of molecular
medicine 75, no. 4 (1997) 239-241.
* Tomoko Ohta and John Gillespie, “Development of
Neutral and Nearly Neutral Theories,” Theoretical
Population Biology 49 (1996) 128-142.
Library Tour
12:-2 Lunch and small group meetings
2-5 Molecular Systematics
Joel Hagen
Reading:
* W. Fitch. and E. Margoliash. "Construction of phylogenetic
trees" Science 155 (1967) 279 284.
* Joel Hagen, "The Statistical Frame of Mind in Systematic
Biology from Quantitative Zoology to Biometry," Journal
of the History of Biology 36 (2003): 353-384.
* Linus Pauling and Emile Zuckerkandl, "Chemical Paleogenetics:
'Molecular Restoration' Studies of Extinct Forms of Life,"
Acta Chemica Scandinavica 17 (1963): S9 - S16.
Friday May 21st
9-10:30 Panel on the Origins of Neutral Molecular Evolution
Mike Dietrich, Dick Lewontin, William Provine and Edna Suarez
Reading:
* Richard Lewontin, The Genetic Basis of Evolutionary Change.
.New York, NY: Columbia University Press, 1974, Chapter
5, pp. 189-271.
* Michael R. Dietrich, "The Origins of the Neutral
Theory of Molecular Evolution", Journal of the History
of Biology 27(1994):21-59.
* Edna Suarez, and Anna Barahona, “The experimental
roots of the neutral theory of molecular evolution,".History
and Philosophy of the Life Sciences 18 (1996):55-81.
10:30 –12 The Development of the Neutral and Nearly
Neutral Theories
Will Provine
Reading:
* Motoo Kimura, "Evolutionary Rate at the Molecular
Level," Nature 217 (1968), 624-626.
* Jack King and Thomas Jukes, "Non-Darwinian Evolution,"
Science 164 (1969), 788- 798.
* Tomoko Ohta, “Slightly Deleterious Mutant Substitutions
in Evolution,” Nature 246 (1973) 96-98.
* Tomoko Ohta, “The Nearly Neutral Theory of Molecular
Evolution,” Annual Review of Ecology and Systematics
23 (1992) 263-286.
* William Provine, “Western Geneticists “Discover”
Kimura,” Journal of Genetics 75 (1996) 9-18.
* James F. Crow, “Motoo Kimura: Student, Colleague,
and Friend,” Journal of Genetics 75 (1996) 5-8.
* Tomoko Steen, “Always an Eccentric?: A Brief Biography
of Motoo Kimura,” Journal of Genetics 75 (1996) 19-26.
12:-2 Lunch and small group meetings
2-5 The Neutralist-Selectionist Controversy
Will Provine, Dick Lewontin, and Roger Milkman
Reading:
* Motoo Kimura, "DNA and the Neutral Theory,"
Philosophical Transactions of the Royal Socety of London,
Series B, Biological Sciences. 312 (1986) 343-354.
* Motoo Kimura and Tomoko Ohta, "On Some Principles Governing
Molecular Evolution,"Proceedings of the National Academy
of Sciences USA 71 (1974) 2848-2852.
Saturday May 22nd
9-12 Modeling and Testing Neutrality and Selection
Mike Dietrich and Dick Lewontin
Reading:
* R. C. Lewontin and J. Krakauer, “Distribution of
Gene Frequency as a Test of the Theory of the Selective
Neutrality of Polymorphisms,” Genetics 74 (1973) 175-195.
* M. Kreitman, “Methods to Detect Selection in Populations
with Applications to the Human,” Annual Review of
Genomics and Human Genetics 1 (2000) 539-569.
12:-2 Lunch and small group meetings
2-5 Techniques and Experimentation
Edna Suarez
Reading:
* D. Giacomoni, "The origin of DNA-RNA Hybridization",
Journal of the History of Biology 26 (1993):89-97.
* L. Kay, "Laboratory technology and Biological knowledge:
the Tisselius Electrophotretic Apparatus, 1930-1945,"
History and Philosophy of the Life Sciences 10 (1988):51-72
* Edna Suarez, "Satellite-DNA: a case study for the
evolution of experimental techniques," Studies in the
History and Philosophy of Biology and Biomedical Science
32 (2001):31-57.
Sunday May 23rd Break. No seminar meetings
Monday May 24th
9-12 Molecular Evolution and Microbial Phylogeny
Jan Sapp
Reading:
* Jan Sapp, “Molecular Evolution and Microbial Phylogeny,”
in Genesis. New York, NY: Oxford University Press, 2003,
pp. 217-233.
* C.R. Woese, O. Kandler and M.L. Wheelis, "Towards
a Natural System of Organisms: Proposal for the Domains
Archaea, Bacteria, and Eucarya,"Proceedings of the
National Academy of Sciences USA 87
(1990):4576-4579..
* E. Mayr, "Two Empires or Three?" Proceedings
of the National Academy of Sciences USA 95 (1998):9720-9723
* C.R. Woese, "The Universal Ancestor," Proceedings
of the National Academy of Sciences USA 95 (1998): 6854-6859.
* C.R. Woese, "Default Taxonomy; Ernst Mayr's View
of the Microbial World," Proceedings of the National
Academy of Sciences USA 95 (1998): 11043-11046.
* W.F. Doolittle, "Evolution, Uprooting the Tree of
Life," Scientific American 282 (2000): 90-95
12:-2 Lunch and small group meetings
2-5 Microbial Evolution
Carl Woese and Jan Sapp
Tuesday May 25th
9-12 Microbial Evolution
Mitch Sogin
Reading:
M. L. Sogin, J. D. Silberman, G. Hinkle, and H. G. Morrison,
"Problems with Molecular Diversity in the Eukarya,"
Society for General Microbiology Symposium 54: Evolution
of Microbial Life, ed. D. McL. Roberts, P. Sharp, G.
Alderson and M.A. Collins. Cambridge University Press, 1996.
pp. 167-184.
12:-2 Lunch and small group meetings
2-5 Assessing the Impact of Molecular Biology on Evolution
Mike Dietrich and John Beatty
Lobster Dinner
Wednesday May 26th Departure.
This page was written by Michael Dietrich. Last updated May
3, 2004.
|
