Other Research Projects: Apollo Bioinformatics Materials Research Physics of Scale

       Molecular Evolution Activities

 

The Infinite Alleles Model The Charge Ladder Model The Infinite Sites Model Models of Sequence Evolution Jukes/Cantor Model Kimura Two-parameter Model Equal-Input Model Kimura Three Substitution Type Model Felsenstein PHYLIP Model General Time Reversible Model HKY Model Tamura and Nei Model SYM Model

Models of Sequence Evolution Jukes/Cantor Model (JC) 1969 This is a one parameter model which assumes that the bases occur with equal frequency and the rate of substitution from one base to any other is the same. A T C G A - α α α T α - α α C α α - α G α α α - Articulated by Thomas Jukes and C. R. Cantor in 1969, the Jukes/Cantor model was the simplest possible model of sequence evolution. Until DNA sequence data became more common, the Jukes/Cantor model was the only model of sequence evolution. References: T. H. Jukes and C. R. Cantor, "Evolution of Protein Molecules," in Munro (ed.), Mammalian Protein Metabolism. New York: Academic Press, 1969, pp. 21-132.

This page was last updated on 21 February 2002 by Michael Dietrich.