Molecular Evolution Activities

Modeling Molecular Evolution
 

Modeling Molecular Evolution

Models are representations of natural systems. While they often may be partial and abstract, they are crucially important instruments of scientific research.

Molecular evolution is marked by a number of distinctive models of molecular evolutionary processes as well as important approaches to modeling, such as Kimura's diffusion equation approach.

These pages will consider some of the fundamental models of mutation as well as models of sequence evolution commonly used with DNA sequence data.

Consideration of models of molecular evolution raise a number of important issues concerning model construction and innovation, the relationship between models and theories, such the neutral theory of molecular evolution, and the relationship between models and experimental data. In particular, the history of modeling molecular evolution reflects the effort to match models with available types of data. As a result the history of different models parrallels the spread of techniques such as electrophoresis and DNA sequencing. As these techniques became predominant sources of data, models of molecular evolution had to be created to take advantage of the particular form of data being generated.

 

 

 
 

Modeling Molecular Evolution