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 James
Crow is Professor Emeritus of Genetics at University of
Wisconsin, where he has taught since 1948. During his years
at Wisconsin, Crow has served as chairman of the Department
of Medical Genetics and the Laboratory of Genetics. He also
served as Acting Dean of the UW Medical School for 2 years.
Additionally, he has been President of the Genetics Society
of America and the American Society of Human Genetics. Crow
received his Ph.D. from University of Texas, Austin in 1941
and has been studying the population genetics of Drosophila
and humans ever since. His research has ranged from investigations
of the genetics of DDT resistance to the effects of small
mutations on the overall fitness of populations. Crow has
made numerous contributions to genetics, including: playing
a significant role in the development of the concept of genetic
load; writing the popular "Genetics Notes" guide for beginning
genetics students (which has gone through eight editions and
has been translated into several languages); and co-authoring
the classic population genetics textbook, An Introduction
to Population Genetics Theory (1970), with Motoo Kimura.
Crow has also
spent much of his career tackling profoundly difficult issues
at the intersection of science and society. Indeed, from 1955-1983,
he served on various National Academy of Science committees
that focused on the biological effects of ionizing radiation.
Recently, he turned his attention to the development of genetic
identification technologies that are used to determine paternity
and convict criminals. From 1994-1996, he chaired the NAS's
Committee on DNA Technology in Forensic Science; and from
1998-2000, he chaired the Department of Justice's Working
Group on the Future of DNA Technology. A truly interdisciplinary
scholar, Crow has also made significant contributions to the
literature on history of genetics. Since 1987, Crow has regularly
contributed to, and served as co-editor of, the "Perspectives:
Anecdotal, Historical, and Critical Commentaries on Genetics"
section of Genetics (several essays written for this column
were recently collected and published as an edited volume
by University of Wisconsin Press). In addition, he has also
published several articles in peer-reviewed historical journals.
Crow is also an accomplished musician, and performed with
the Madison Symphony Orchestra from 1949-1994. He served as
President of the MSO from 1984-1986.
Link
to Crow's personal webpage
Selected
Bibliography:
- J.F. Crow and A.P. Mange, "Measurement of inbreeding
from the frequency of marriages between persons of the same
surname," Eugenics Quarterly 12 (1965): 199-203.
- J.F. Crow and J. Felsenstein, "The effect of assortative
mating on the genetic composition of a population,"
Eugenics Quarterly 15 (1968): 85-97.
- J.F. Crow, "Rates of genetic change under selection,"
PNAS 59 (1968): 655-61.
- M. Kimura and J.F. Crow, "Natural selection and gene
substitution," Genetical Research 13 (1969):127-41.
- J.F. Crow and M. Kimura, An Introduction to Population
Genetic Theory (New York: Harper and Row, 1970).
- M.W. Feldman and J.F. Crow, "On quasilinkage equilibrium
and the fundamental theorem of natural selection,"
Theoretical Population Biology 1 (1970):371-91.
- J.F. Crow and T. Maruyama, "The number of neutral
alleles maintained in a finite, geographically structured
population," Theoretical Population Biology
2(1971): 437-53.
- M. Kimura and J.F. Crow, "The effective number of
a population with overlapping generations: a correction
and further discussion," American Journal of Human
Genetics 24 (1972):1-10.
- J.F. Crow, "The dilemma of nearly neutral mutations.
How important are they for evolution and human welfare?,"
Journal of Heredity 63 (1972):306-16.
- T. Nagylaki and J.F. Crow, "Continuous selective
models," Theoretical Population Biology 5 (1974):
257-83.
- C.H. Langley and J.F. Crow, "The direction of linkage
disequilibrium," Genetics 78 (1974): 937-41.
- J.F. Crow, "The theory of neutral and weakly selected
genes," Federation Proceedings 35 (1976): 2083-6.
- M.J. Simmons and J.F. Crow, "Mutations affecting
fitness in Drosophila populations," Annual Review
of Genetics 11 (1977): 49-78.
- M. Kimura and J.F. Crow, "Effect of overall phenotypic
selection on genetic change at individual loci," PNAS
75 (1978): 6168-71.
- J.F. Crow, "Genes that violate Mendel's rules,"
Scientific American 240 (1979): 134-43. 146, 1979
Feb.
- J.F. Crow and C. Denniston, "The mutation component
of genetic damage," Science 212 (1981): 888-93.
- J.F. Crow and K. Aoki, "Group selection for a polygenic
behavioral trait: a differential proliferation model,"
PNAS 79 (1982): 2628-31.
- J.F. Crow, "Sewall Wright, the scientist and the
man," Perspectives in Biology and Medicine 25
(1982): 279-94.
- J.F. Crow, "The Neutrality-Selection Controversy
in the history of evolution and population genetics,"
in Ohta and Aoki (eds.), Population Genetics and Molecular
Evolution (Tokyo: Japanese Scientific Press, 1985),
pp. 1-18.
- J.F. Crow, "Population genetics history: a personal
view," Annual Review of Genetics 21 (1987):
1-22.
- J.F. Crow, "Muller, Dobzhanksy and Overdominance,"
Journal of the History of Biology 20 (1987): 351-380.
- James Crow,
"Twenty-Five Years Ago in Genetics: Motoo Kimura and Molecular
Evolution," Genetics 119 (1987), pp. ?
- J.F. Crow, "Eighty years ago: the beginnings of population
genetics," Genetics 119 (1988): 473-6.
- J.F. Crow, "The ultraselfish gene," Genetics
118 (1988): 389-91.
- J.F. Crow, "Sewall Wright (1889-1988)," Genetics
119 (1988): 1-4.
- James Crow,
"Twenty-Five Years Ago in Genetics: The Infinite Alleles
Model," Genetics 121 (1989): 631-4.
- J.F. Crow, "Concern for environmental mutagens: some
personal reminiscences," Environmental and Molecular
Mutagenesis 16(1989): 7-10.
- J.F. Crow, "Fisher's contributions to genetics and
evolution," Theoretical Population Biology 38
(1990): 263-75.
- J.F. Crow, "Anecdotal, historical and critical commentaries
on genetics. R. A. Fisher, a centennial view," Genetics
124 (1990): 207-211.
- J.F. Crow, "Centennial: J. B. S. Haldane, 1892-1964,"
Genetics 130 (1992): 1-6.
- James Crow,
"Twenty-Five Years Ago in Genetics: Identical Triplets,"
Genetics 124 (1992), pp. 395-398.
- A. S. Kondrashov and J.F. Crow, "A molecular approach
to estimating the human deleterious mutation rate,"
Human Mutation 2 (1993): 229-34.
- J.F. Crow, "Advantages of sexual reproduction,"
Developmental Genetics 15 (1994): 205-13.
- J.F. Crow, "Motoo Kimura (1924-1994)," Genetics,
140 (1995): 1-5.
- James Crow,
"Memories of Moto," Theoretical Population Genetics 49 (1996):
122-127.
- J.F. Crow, "Molecular evolution--who is in the driver's
seat?," Nature Genetics 17(1997): 129-30.
- J.F. Crow, "Thomas H. Jukes (1906-1999), Genetics
154 (2000): 955-6.
- J.F. Crow, "The beanbag lives on," Nature
409 (2001): 771.
This page was written by Jay Aronson on August 27, 2001.
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