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The competitive inhibition of of the urease-catalyzed hydrolysis of urea by phosphate

Harmon, Kent M. and Niemann, Carl (1949) The competitive inhibition of of the urease-catalyzed hydrolysis of urea by phosphate. Journal of Biological Chemistry, 177 (2). pp. 601-605. ISSN 0021-9258. http://resolver.caltech.edu/CaltechAUTHORS:HARjbc49a

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Abstract

The urease-catalyzed hydrolysis of urea has been found to be competitively inhibited by phosphate at pH 7.0 and 25°. The Michaelis constant of the urea-urease system has been found to be approximately 0.003 M urea and the comparable constant defining the phosphate-urease system 0.035 M phosphate.


Item Type:Article
Additional Information:Copyright © 1949 by the American Society of Biological Chemists (Received for publication, August 31, 1948) [K.M.H. was a] National Research Council Predoctoral Fellow. Gates and Crellin Laboratories of Chemistry, Contribution No. 1238.
Record Number:CaltechAUTHORS:HARjbc49a
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:HARjbc49a
Alternative URL:http://www.jbc.org/content/vol177/issue2/index.shtml
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:5840
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:04 Nov 2006
Last Modified:26 Dec 2012 09:15

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