Ward, Gary E. and Brokaw, Charles J. and Garbers, David L. and Vacquier, Victor D. (1985) Chemotaxis of Arbacia punctulata spermatozoa to resact, a peptide from the egg jelly layer. Journal of Cell Biology, 101 (6). pp. 2324-2329. ISSN 0021-9525 http://resolver.caltech.edu/CaltechAUTHORS:WARjcb85
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Resact, a peptide of known sequence isolated from the jelly layer of Arbacia punctulata eggs, is a potent chemoattractant for A. punctulata spermatozoa. The chemotactic response is concentration dependent, is abolished by pretreatment of the spermatozoa with resact, and shows an absolute requirement for millimolar external calcium. A. punctulata spermatozoa do not respond to speract, a peptide isolated from the jelly layer of Strongylocentrotus purpuratus eggs. This is the first report of animal sperm chemotaxis in response to a defined egg-derived molecule.
|Additional Information:||Copyright © 1985 by The Rockefeller University Press Received for publication 12 June 1985, and in revised form 22 August 1985. We thank Dr. Hiromi Shimomura for his generous gift of synthetic resact and Sandee Nagayama for technical assistance. This work was supported by National Institutes of Health grants HD-12896 to V.D. Vacquier, GM-18711 to C.J. Brokaw, and HD-10254 to D.L. Garbers.|
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|Deposited On:||27 Nov 2006|
|Last Modified:||26 Dec 2012 09:18|
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