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Genomic function during the lampbrush chromosome stage of amphibian oogenesis

Davidson, Eric H. and Crippa, Marco and Kramer, Fred R. and Mirsky, Alfred E. (1966) Genomic function during the lampbrush chromosome stage of amphibian oogenesis. Proceedings of the National Academy of Sciences of the United States of America, 56 (3). pp. 856-863. ISSN 0027-8424.

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Throughout its lengthy developmental history the disposition of the genetic material in the amphibian oocyte nucleus differs from that in other cell types. The chromosomes in the oocyte nucleus, arrested for the whole of oogenesis at the prophase of the first meiotic division, are known to contain at least the tetraploid amount of DNA.(1,2) Oogenesis in amphibia requires months or even years to complete, depending on the species.

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Additional Information:© 1966 by the National Academy of Sciences. Communicated July 1, 1966. The authors gratefully acknowledge the assistance of Dr. James Schwartz in the preparation and utilization of the S-30 system, and the generosity of the laboratory of Dr. Norton Zinder in supplying us with F2 coliphage. This investigation would not have been possible without the expert and conscientious technical assistance of Mr. R.J. Finney. This investigation was supported in part by American Cancer Society grants E-334 and E-334A.
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:7563
Deposited By: Tony Diaz
Deposited On:05 Mar 2007
Last Modified:14 Nov 2014 19:19

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