Davis, Ronald W. and Davidson, Norman (1968) Electron-microscopic visualization of deletion mutations. Proceedings of the National Academy of Sciences of the United States of America, 60 (1). pp. 243-250. ISSN 0027-8424 http://resolver.caltech.edu/CaltechAUTHORS:DAVpnas68a
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Deletion mutants of λ coliphage were discovered by Kellenberger, Zichichi, and Weigle.(1) The deletions can be mapped by genetic recombination experiments. It is not known if the recombination maps thus obtained give the true physical position of the deletions. The present paper describes a method for mapping deletion mutations with the electron microscope, thus obtaining the physical position of the deletion.
|Additional Information:||© 1968 by the National Academy of Sciences. Communicated February 12, 1968. We are grateful to Dr. Robert Huskey for his help and phage stocks, to Dr. James G. Wetmur for advice on annealing conditions, and to Dr. Jean Weigle for his patient guidance and counsel in many matters. This work has been supported by research grant GM 10991 and training grant GM 1262 from the U.S. Public Health Service.|
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|Deposited By:||Tony Diaz|
|Deposited On:||06 Mar 2007|
|Last Modified:||26 Dec 2012 09:32|
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