Sturtevant, A. H. and Schultz, Jack (1931) The inadequacy of the sub-gene hypothesis of the nature of the scute allelomorphs of Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 17 (5). pp. 265-270. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:STUpnas31
See Usage Policy.
Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:STUpnas31
In a series of papers, Serebrovsky (1930), Dubinin (1929), Agol (1930) and their colleagues have described an extremely interesting group of bristle-reducing mutant genes lying at the scute locus of the X-chromosome of Drosophila melanogaster. As a result of their careful studies of this material, they have elaborated an interpretation of the situation. According to this hypothesis, the normal allelomorph of the scute genes is not a single unit, but is made up of a series of "sub-genes" arranged in linear order, each sub-gene being concerned with the development of one or of a few bristles on the fly. The scute mutations involve changes in blocks of these sub-genes, but of different blocks. Scute 11, for example, represents mutation of a few sub-genes at the left end of the series; scute 4, of practically all the sub-genes not affected by scute 11; scute 5 of a few sub-genes near the right end. All the known allelomorphs may be described in such terms.
|Additional Information:||© 1931 by the National Academy of Sciences. Communicated April 2, 1931. We are greatly indebted to Prof. A. S. Serebrovsky for his generosity in sending to this laboratory stocks of scute 2, scute 3, scute 4, scute 5, scute 6, scute 7 and scute 11, as well as of several other interesting new types. The other types examined were scute 1, scute B3 (the scute 3 of Morgan, Bridges and Sturtevant, 1925), achaete, and scute D (recently obtained by Prof. T. Dobzhansky in x-ray experiments, and very kindly given to us by him). It is a pleasure to express our indebtedness to Professor H. J. Muller, to Professor T. Dobzhansky and to L. V. Morgan, for their kindness in supplying us with stocks of the various duplications.|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||13 Mar 2007|
|Last Modified:||26 Dec 2012 09:33|
Repository Staff Only: item control page