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WormBase: a multi-species resource for nematode biology and genomics

Harris, Todd W. and Chen, Nansheng and Cunningham, Fiona and Tello-Ruiz, Marcela and Antoshechkin, Igor and Bastiani, Carol and Bieri, Tamberlyn and Blasiar, Darin and Bradnam, Keith and Chan, Juancarlos and Chen, Chao-Kung and Chen, Wen J. and Davis, Paul and Kenny, Eimear and Kishore, Ranjana and Lawson, Daniel and Lee, Raymond and Müller, Hans-Michael and Nakamura, Cecilia and Ozersky, Philip and Petcherski, Andrei and Rogers, Anthony and Sabo, Aniko and Schwarz, Erich M. and Van Auken, Kimberly and Wang, Qinghua and Durbin, Richard and Spieth, John and Sternberg, Paul W. and Stein, Lincoln D. (2004) WormBase: a multi-species resource for nematode biology and genomics. Nucleic Acids Research, 32 (Databa). D411-D417. ISSN 0305-1048. http://resolver.caltech.edu/CaltechAUTHORS:HARnar04

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Abstract

WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with extensively annotated views of the genome. The WormBase Consortium continues to expand the biological scope and utility of WormBase with the inclusion of large-scale genomic analyses, through active data and literature curation, through new analysis and visualization tools, and through refinement of the user interface. Over the past year, the nearly complete genomic sequence and comparative analyses of the closely related species Caenorhabditis briggsae have been integrated into WormBase, including gene predictions, ortholog assignments and a new synteny viewer to display the relationships between the two species. Extensive site-wide refinement of the user interface now provides quick access to the most frequently accessed resources and a consistent browsing experience across the site. Unified single-page views now provide complete summaries of commonly accessed entries like genes. These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system.


Item Type:Article
Additional Information:© 2004 Oxford University Press Received September 15, 2003; Revised and Accepted September 25, 2003 WormBase is supported by grant P41-HG02223 from the US National Human Genome Research Institute and the British Medical Research Council. P.W.S. is an Investigator with the Howard Hughes Medical Institute. The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors. On a closing note, we welcome the submission of data sets, corrections to existing data, and your comments, questions and suggestions (wormbase-help@wormbase.org).
Record Number:CaltechAUTHORS:HARnar04
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:HARnar04
Alternative URL:http://dx.doi.org/10.1093/nar/gkh066
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:814
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:08 Oct 2005
Last Modified:26 Dec 2012 08:41

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