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A suppressor in Neurospora and its use as evidence for allelism

Houlahan, Mary B. and Mitchell, Herschel K. (1947) A suppressor in Neurospora and its use as evidence for allelism. Proceedings of the National Academy of Sciences of the United States of America, 33 (8). pp. 223-229. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:HOUpnas47

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Abstract

In Drosophila recessive mutations have been observed which suppress the effect of specific mutations at other loci. Thus an individual, homozygous for a suppressor gene in the mutant form and for the mutant gene upon which the suppressor acts, is phenotypically wild type, or nearly so. Suppressors of black,(1) purple,(2,3) sable(4) and vermilion(4, 5) are among those, which have been reported. In the vermilion case there is evidence(5) which shows that the action of the suppressor is to restore v+ substance (kynurenine), the formation of which is prevented when the mutant gene vermilion is present in the homozygous condition.


Item Type:Article
Additional Information:© 1947 by the National Academy of Sciences. Communicated June 10, 1947. Work supported by grants from the Rockefeller Foundation.
Record Number:CaltechAUTHORS:HOUpnas47
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:HOUpnas47
Alternative URL:http://www.pnas.org/cgi/reprint/33/8/223
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:8215
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:01 Aug 2007
Last Modified:14 Nov 2014 19:20

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