Komano, Tohru and Knippers, Rolf and Sinsheimer, Robert L. (1968) The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA. Proceedings of the National Academy of Sciences of the United States of America, 59 (3). pp. 911-916. ISSN 0027-8424 http://resolver.caltech.edu/CaltechAUTHORS:KOMpnas68
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Abstract
In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during the subsequent period of single-strand DNA synthesis, while half remained in RF molecules. In this paper experiments are presented which permit a definition of the label remaining in the RF and which clarify the role of the RF in the synthesis of the progeny single-stranded DNA.
| Item Type: | Article |
|---|---|
| Additional Information: | © 1968 by the National Academy of Sciences. Communicated December 20, 1967. We are indebted to Dr. M. Goulian for a generous gift of purified exonuclease III and to Mrs. Louise Wilson for technical assistance. This research was supported in part by grant GM 13554 from the U.S. Public Health Service. |
| Record Number: | CaltechAUTHORS:KOMpnas68 |
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:KOMpnas68 |
| Alternative URL: | http://www.pnas.org/cgi/reprint/59/3/911 |
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 8592 |
| Collection: | CaltechAUTHORS |
| Deposited By: | Tony Diaz |
| Deposited On: | 21 Aug 2007 |
| Last Modified: | 26 Dec 2012 09:40 |
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