Bachvarova, R. and Davidson, E. H. and Allfrey, V. G. and Mirsky, A. E. (1966) Activation of RNA Synthesis Associated with Gastrulation. Proceedings of the National Academy of Sciences of the United States of America, 55 (2). pp. 358-365. ISSN 0027-8424. PMCID PMC224149. http://resolver.caltech.edu/CaltechAUTHORS:BACpnas66
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Gastrulation in the amphibian embryo marks the onset of widespread, de novo cell differentiation. In this communication we present the results of a radioautographic and biochemical study of gene activity as gastrulation takes place in Xenopus laevis. We have found that gene activation occurs abruptly within a 1-hr period preceding the onset of gastrulation and that most of the newly synthesized RNA resulting from this activation appears to be messenger RNA.
|Additional Information:||Copyright © 1966 by the National Academy of Sciences. Communicated December 6, 1965. This investigation was supported in part by American Cancer Society grant E-334.|
|PubMed Central ID:||PMC224149|
|Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Archive Administrator|
|Deposited On:||03 Oct 2007|
|Last Modified:||17 Dec 2015 00:41|
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