Glaser, Michael and Simpkins, Henry and Singer, S. J. and Sheetz, Michael and Chan, Sunney I. (1970) On the interactions of lipids and proteins in the red blood cell membrane. Proceedings of the National Academy of Sciences of the United States of America, 65 (3). pp. 721-728. ISSN 0027-8424 http://resolver.caltech.edu/CaltechAUTHORS:GLApnas70
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Abstract
The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the proteins of the membranes can change structure independently of one another, suggesting a mosaic pattern for the organization of the lipids and proteins in membranes.
| Item Type: | Article |
|---|---|
| Additional Information: | © 1970 by the National Academy of Sciences. Communicated December 12, 1969. This work was supported in part by U.S.P.H.S. grant GM-15971 to S.J. Singer and U.S.P.H.S. grant GM-14523 and NSF grant GP-8540 to S.I. Chan (Caltech). [M.S. was a] National Institute of Health Predoctoral Trainee, 1969-1970. A.A. Noyes Laboratory of Chemical Physics, Contribution No. 3977. |
| Record Number: | CaltechAUTHORS:GLApnas70 |
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:GLApnas70 |
| Alternative URL: | http://www.pnas.org/cgi/content/abstract/65/3/721 |
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 8966 |
| Collection: | CaltechAUTHORS |
| Deposited By: | Tony Diaz |
| Deposited On: | 09 Oct 2007 |
| Last Modified: | 26 Dec 2012 09:44 |
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