Vikalo, H. and Hassibi, B. and Hassibi, A. (2007) On joint maximum-likelihood estimation of PCR efficiency and initial amount of target. In: IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS 2006), College Station, TX, 28-30 May 2006. IEEE , Piscataway, NJ, pp. 47-48. ISBN 1-4244-0385-5 http://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06
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Abstract
We consider the problem of estimating unknown parameters of the real-time polymerase chain reaction (RTPCR) from noisy observations. The joint ML estimator of the RT-PCR efficiency and the initial number of DNA target molecules is derived. The mean-square error performance of the estimator is studied via simulations. The simulation results indicate that the proposed estimator significantly outperforms a competing technique.
| Item Type: | Book Section |
|---|---|
| Additional Information: | © Copyright 2006 IEEE. Reprinted with permission. [Posted online: 2007-04-30] |
| Record Number: | CaltechAUTHORS:VIKgensips06 |
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:VIKgensips06 |
| Alternative URL: | http://dx.doi.org/10.1109/GENSIPS.2006.353149 |
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 9074 |
| Collection: | CaltechAUTHORS |
| Deposited By: | Archive Administrator |
| Deposited On: | 25 Oct 2007 |
| Last Modified: | 26 Dec 2012 09:45 |
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