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Purine binding to dinucleotides: Evidence for base stacking and insertion

Chan, Sunney I. and Bangerter, Benedict W. and Peter, Heinrich H. (1966) Purine binding to dinucleotides: Evidence for base stacking and insertion. Proceedings of the National Academy of Sciences of the United States of America, 55 (4). pp. 720-727. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:CHApnas66

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Abstract

In an effort to understand the factors which may contribute to the stabilization of nucleic acids as well as the basic mechanism of the recognition process involved in the enzymatic replication of nucleic acids in vitro, we have embarked upon a systematic study of the interaction of biological bases and nucleosides with simple oligonucleotides by proton magnetic resonance. We wish to report here results which we have obtained on the interaction of purine with the following 3' --> 5'-dinucleotides: TpT, TpdU, and dUpT (T = thymidine, dU = 2'-deoxyuridine).


Item Type:Article
Additional Information:Copyright © 1966 by the National Academy of Sciences. Communicated by John D. Roberts, February 24, 1966. Gates and Crellin Laboratories of Chemistry, Contribution no. 3321
Record Number:CaltechAUTHORS:CHApnas66
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:CHApnas66
Alternative URL:http://www.pnas.org/cgi/content/abstract/55/4/720
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:949
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:15 Nov 2005
Last Modified:26 Dec 2012 08:42

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