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Chen, Keqin and Arnold, Frances H. (1993) Tuning the Activity of an Enzyme for Unusual Environments: Sequential Random Mutagenesis of Subtilisin E for Catalysis in Dimethylformamide. Proceedings of the National Academy of Sciences of the United States of America, 90 (6). pp. 5618-5622. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:CHEpnas93